Two children, Ignacio and Enrique, know love, the movies and fear in a religious school at the beginning of the 1960s. Father Manolo, director of the school and its professor of literature, is witness to and part of these discoveries. The three are followed through the next few decades, their reunion marking life and death.
Pepa resolves to kill herself with a batch of sleeping-pill-laced gazpacho after her lover leaves her. Fortunately, she is interrupted by a deliciously chaotic series of events.
A scorned ex-convict forces himself into the lives of the couple who put him behind bars.
In the 1970s, a foundling lad, Patrick "Kitten" Braden, comes of age by leaving his Irish town for London, in part to look for his mother and in part because his transgender nature is beyond the town's understanding.
Raimunda (Penélope Cruz) works and lives Madrid with her husband Paco and daughter Paula. Her sister Sole (Lola Dueñas) lives nearby and they both miss their mother Irene (Carmen Maura), who died several years ago in a house fire along with their father. A former neighbor from their hometown reports that she has seen the ghost of Irene and both daughters do not believe her. After a murder and a family tragedy, Irene's spirit materializes around her daughters to help comfort them.
Bob Hughes is the leader of a "family" of drug addicts consisting of his wife, Dianne, and another couple who feed their habit by robbing drug stores as they travel across the country.
Company centers on Bobby, a confirmed bachelor, celebrating his 35th birthday with his ten closest friends, who happen to be five couples.
Originally entitled Threes, its plot revolves around Bobby (a single man unable to commit fully to a steady relationship, let alone marriage), the five married couples who are his best friends, and his three girlfriends. Unlike most book musicals, which follow a clearly delineated plot, this movie is a concept musical composed of short vignettes, presented in no particular chronological order, linked by a celebration for Bobby's 35th birthday.